Midwest-focused M25 rolls out new venture partners across region, adding high-profile STL founder
March 13, 2025 | Tommy Felts
CHICAGO — An influential venture capital firm with portfolio companies in Kansas City and across the region on Thursday announced a St. Louis serial entrepreneur as the latest venture partner joining its mission to back a new generation of Midwest unicorns.
Guy Friedman, co-founder and CEO of SteadyMD, brings an invaluable founder’s perspective — plus a strong track record of launching, scaling and raising capital — to M25, said Victor Gutwein, managing partner at the Chicago-based venture capital firm, which was an early investor in Friedman’s company.
The news comes as M25 launches a strategy to gradually bring on new venture partners from across the Midwest, having previously announced legaltech entrepreneur Brian Powers in Indianapolis.
“St. Louis has been a very strong ecosystem for startups, and we didn’t want to miss anything, so we needed a guy or gal here,” said Gutwein, detailing Friedman’s selection. “Well, we found our Guy — SteadyMD was one of our first big success stories here so his deep network and experience in multiple industries will give us great access and expertise.”
M25 has been an active investor in Missouri, having backed 9 startups in the Greater St. Louis area and 13 total across the state, including Ryvit (acquired by Trimble in 2023), Summersalt and Kansas City’s Super Dispatch and backstitch.
Click here to explore M25’s portfolio.
With Friedman’s leadership and connections in the local startup scene, M25 aims to deepen its Missouri presence and support even more promising founders building in the Show Me State, the firm said.
As venture partner, Friedman will help source and evaluate deals, dive deep into due diligence and mentor founders post-investment — leveraging his firsthand experience of building and scaling high-growth startups.
Before SteadyMD — a category-defining virtual healthcare solution that has already raised $60 million and has seen millions of patients across its diverse set of enterprise clients — Friedman saw the exit of his startup HigherNext (acquired by ProctorU in 2013).
“I’ve been working with Victor Gutwein, Mike Asem and the team at M25 since the early days of SteadyMD — they’ve created a true community with their founders and I know they are a ‘first call’ for many of their portfolio company CEOs,” said Friedman. “I’m excited to work with them to help some of the most innovative companies in the world.”

2025 Startups to Watch
stats here
Related Posts on Startland News
How this founder’s hobby (plus a little trouble) became Oak Park retail incubator’s biggest success story
“Big Chunky Blankets” — soft as a baby’s cheek and custom knitted in any color of the rainbow — folded into the foundation of what would become Maryann Nzioki Hult’s resilient, nearly pandemic-proof foray into entrepreneurship. They put local Tabu Knits on the online map of must-have-items, and then became the seed of two Johnson…
Big win for UMKC: Unlocking top tier research status gives KC new competitive edge
A new milestone for the University of Missouri-Kansas City — achieving status as Kansas City’s first Carnegie R1 research institution — is expected to help boost the region’s ability to start, grow and scale more startups, leaders said this week, emphasizing the role university-led research plays in innovation across industries and communities. “It’s absolutely massive…
KC Bier Co building new 30,000-square-foot urban beer garden; founder brewing a space for all
A Kansas City-built, German-style brewery is expanding to Lenexa — bringing an authentic Bavarian beer garden experience to Johnson County, said founder Steve Holle. Developed in partnership with West Star Development, the new KC Bier Co. venue will feature a large outdoor space, an indoor restaurant, private event areas, and a stage for live music…
Founder Problems: Podcast captures the ‘messy middle’ you don’t see on entrepreneurs’ highlight reels
A new Kansas City-based podcast is skipping over the fairy tale stories of founding a startup; instead diving straight into the messy parts, the hosts shared. Founder Problems — hosted by local entrepreneurs Sarah Schumacher, Zach Oshinbanjo, and Lee Zuvanich — is embracing the aspects of starting and running a business that no one wants…


