Midwest-focused M25 rolls out new venture partners across region, adding high-profile STL founder
March 13, 2025 | Tommy Felts
CHICAGO — An influential venture capital firm with portfolio companies in Kansas City and across the region on Thursday announced a St. Louis serial entrepreneur as the latest venture partner joining its mission to back a new generation of Midwest unicorns.
Guy Friedman, co-founder and CEO of SteadyMD, brings an invaluable founder’s perspective — plus a strong track record of launching, scaling and raising capital — to M25, said Victor Gutwein, managing partner at the Chicago-based venture capital firm, which was an early investor in Friedman’s company.
The news comes as M25 launches a strategy to gradually bring on new venture partners from across the Midwest, having previously announced legaltech entrepreneur Brian Powers in Indianapolis.
“St. Louis has been a very strong ecosystem for startups, and we didn’t want to miss anything, so we needed a guy or gal here,” said Gutwein, detailing Friedman’s selection. “Well, we found our Guy — SteadyMD was one of our first big success stories here so his deep network and experience in multiple industries will give us great access and expertise.”
M25 has been an active investor in Missouri, having backed 9 startups in the Greater St. Louis area and 13 total across the state, including Ryvit (acquired by Trimble in 2023), Summersalt and Kansas City’s Super Dispatch and backstitch.
Click here to explore M25’s portfolio.
With Friedman’s leadership and connections in the local startup scene, M25 aims to deepen its Missouri presence and support even more promising founders building in the Show Me State, the firm said.
As venture partner, Friedman will help source and evaluate deals, dive deep into due diligence and mentor founders post-investment — leveraging his firsthand experience of building and scaling high-growth startups.
Before SteadyMD — a category-defining virtual healthcare solution that has already raised $60 million and has seen millions of patients across its diverse set of enterprise clients — Friedman saw the exit of his startup HigherNext (acquired by ProctorU in 2013).
“I’ve been working with Victor Gutwein, Mike Asem and the team at M25 since the early days of SteadyMD — they’ve created a true community with their founders and I know they are a ‘first call’ for many of their portfolio company CEOs,” said Friedman. “I’m excited to work with them to help some of the most innovative companies in the world.”

2025 Startups to Watch
stats here
Related Posts on Startland News
Innovation Stockyard selects first St. Joe startup for Digital Sandbox
A curbside recycling service is expected to be the first startup to receive Digital Sandbox KC proof-of-concept funding through the Innovation Stockyard incubator. Toss it Curbside, a service with which customers place unwanted items on their curbs to be recycled or donated, plans to use the funds and the St. Joseph-based incubator program to optimize…
Applications open: Sprint Accelerator dialing into ag tech, IoT with 2018 cohort
Investing in startups isn’t just about providing needed capital, Doug Dresslaer said. As the Sprint Accelerator gears up for its fifth year, Dresslaer, managing director of the program, said the accelerator’s 2017 cohort — the first since its move toward establishing corporate partnerships and pivot away from Techstars — proved industry relationships themselves create tremendous value.…
Entrepreneurial inspiration: How a wheelchair freed Wesley Hamilton
Editor’s note: Kansas City fitness and community advocate Wesley Hamilton offered four inspirational tips for entrepreneurs, illustrated by his own remarkable experiences overcoming adversity. Two bullets pierced Wesley Hamilton’s back, confining him to a wheelchair, but freeing his mind, the Kansas City adaptive athlete said. “I found that being shot by someone I never knew…
Show ’em KC hustle! 1 Million Cups needs you to beat Fargo (Video)
Nice shirts. Clever designs. The perfect mix of whimsy and irreverent wordplay. They’d fit in well among the Kansas City apparel scene. Except for one glaring snag: They’re brewed in Fargo. Yeah. That Fargo. And if you don’t want to see them on the backs of KC’s 1 Million Cups team, you’ll make plans to…


