Midwest-focused M25 rolls out new venture partners across region, adding high-profile STL founder
March 13, 2025 | Tommy Felts
CHICAGO — An influential venture capital firm with portfolio companies in Kansas City and across the region on Thursday announced a St. Louis serial entrepreneur as the latest venture partner joining its mission to back a new generation of Midwest unicorns.
Guy Friedman, co-founder and CEO of SteadyMD, brings an invaluable founder’s perspective — plus a strong track record of launching, scaling and raising capital — to M25, said Victor Gutwein, managing partner at the Chicago-based venture capital firm, which was an early investor in Friedman’s company.
The news comes as M25 launches a strategy to gradually bring on new venture partners from across the Midwest, having previously announced legaltech entrepreneur Brian Powers in Indianapolis.
“St. Louis has been a very strong ecosystem for startups, and we didn’t want to miss anything, so we needed a guy or gal here,” said Gutwein, detailing Friedman’s selection. “Well, we found our Guy — SteadyMD was one of our first big success stories here so his deep network and experience in multiple industries will give us great access and expertise.”
M25 has been an active investor in Missouri, having backed 9 startups in the Greater St. Louis area and 13 total across the state, including Ryvit (acquired by Trimble in 2023), Summersalt and Kansas City’s Super Dispatch and backstitch.
Click here to explore M25’s portfolio.
With Friedman’s leadership and connections in the local startup scene, M25 aims to deepen its Missouri presence and support even more promising founders building in the Show Me State, the firm said.
As venture partner, Friedman will help source and evaluate deals, dive deep into due diligence and mentor founders post-investment — leveraging his firsthand experience of building and scaling high-growth startups.
Before SteadyMD — a category-defining virtual healthcare solution that has already raised $60 million and has seen millions of patients across its diverse set of enterprise clients — Friedman saw the exit of his startup HigherNext (acquired by ProctorU in 2013).
“I’ve been working with Victor Gutwein, Mike Asem and the team at M25 since the early days of SteadyMD — they’ve created a true community with their founders and I know they are a ‘first call’ for many of their portfolio company CEOs,” said Friedman. “I’m excited to work with them to help some of the most innovative companies in the world.”

2025 Startups to Watch
stats here
Related Posts on Startland News
$17M Operation Breakthrough expansion to bridge Troost, boost STEM and maker skills
An Operation Breakthrough expansion from the east side of Troost Avenue to the west is about more than jumping across the street, said Mary Esselman. The move will literally bridge a racial and economic dividing line that has persisted for decades. “Bridging Troost is not only a legacy to our founders, but is huge symbolically,…
ClusterTruck sizzles on KC food delivery scene with ‘ghost kitchen’ concept
The innovation cooking within ClusterTruck’s technology makes the rapidly expanding Indianapolis company a fresh take on the restaurant-quality food delivery scene, Christian Moscoso said. “We are a software company with our own ghost kitchens, if you will,” said Moscoso, general manager for ClusterTruck’s new River Market kitchen, which opened in mid-December without a public entrance…
Innovation Exchange returns in 2018 with new partners, topics
One of my favorite parts of journalism is the “Hm!” moment. They are the occasions when reading, watching or listening to a story whose details yield an inborn reaction of fascination or intrigue. They can’t be stopped. When your curiosity piqued, “Hmm!” is an impulse. “The SpaceX Falcon Heavy rocket produced 5 million pounds of…
Sickweather storms market with overfunded $1M crowdfunding campaign amid flu season
An illness forecaster is never more valuable than when the threat of a widespread virus is high. This year’s severe flu season, however, is only one of the leading contributors to Sickweather’s uptick in interest — and its recent oversubscribed $1 million crowdfunding campaign, said founder Graham Dodge. “We learn a lot every cold and…


