M25 rankings: Startup hubs are slowing; why KC could be losing ground to Midwest neighbors
August 13, 2024 | Tommy Felts
Kansas City’s startup scene is walking a fine line between flat and stagnant, said Victor Gutwein, teasing caution and other insights into KC’s No. 11 ranking — a position it’s held since 2022 — on M25’s latest Midwest startup cities list.
“We’re seeing fewer startups (registered in our datasource Pitchbook) than we used to in Kansas City — and that’s worrying,” said Gutwein, founder and managing partner at M25, an influential early-stage venture firm based in Chicago.
Missing from the news: Headlines from Kansas City with hefty multi-million-dollar funding rounds, he noted, with only Sailes’ $5.1 million round (with regional investors KCRise Fund and Tenzing Capital) making a dent.
“Anecdotally at M25, we’ve seen a decrease in startup deal flow from the KC metro region,” he added. “That’s not something to be crazy concerned about — things can come and go in waves and we are also a small/biased sample — but if it continues for multiple years it will be a concerning trend.”
Click here to view the complete rankings from M25.
M25 boasts Kansas City startups SuperDispatch, Zohr, Backstitch and Whipz among its portfolio companies.
“We love investing in Kansas City,” Gutwein said. “And we want to do more.”
The deep-dive Best of The Midwest: Startup City Rankings report — compiled annually by the team at M25 — explores how micro-environments across the Midwest are performing relative to each other based on startup activity, access to resources, and business climate.
“In a year that saw relatively little, the Midwest still had a lot to brag about,” Gutwein said in a blog that discussed overall takeaways from the report (which shows Chicago, Minneapolis and Indianapolis continue to dominate the rankings).
“The past year has seen some lows in venture and startup funding that we haven’t seen for a while. Venture firms are on track to raise the lowest amount of capital since 2013, 38 percent of the venture funds that were actively deploying in 2022 did not make any new investments in 2023, and major startup funding announcements have slowed to a fraction of what they were in the ZIRP (zero interest-rate policy) economy,” he said. “Despite the tough macroeconomic environment of the last 12 months, we have continued to see deals get done in the Midwest that validate investor interest in what the region does best — capital efficient growth in industries that aren’t going anywhere.”
Click here to read more of Gutwein’s insights from the report.
Funding tank running low
A lack of high-dollar funding announcements or new venture funds launched the past 12 months contributed to malaise over Kansas City’s prospects in the rankings, Gutwein said.
He was, however, encouraged that Kansas City’s overall score in the report edged up slightly from 2023 (a score of 25.3 out 64.0, compared to a previous 25.0), and noted the significance of ongoing state support for startups and tech entrepreneurs from such organizations as the Missouri Technology Corporation.
Click here for a closer look at how M25’s rankings and scores are determined.
“But while we are seeing increased activity from MTC, it still pales in comparison to the volume, speed and efficiency that other direct investment programs have like Elevate Ventures in Indiana (which can be 50 percent of a round and invests on a regular cadence in several dozen Indiana startups every year and at every stage) or InvestNebraska, among others,” Gutwein said. “Not to mention Missouri doesn’t have an active angel tax credit or fund-of-funds, which other states have been actively deploying in the past few years.”
St. Louis saw more investment than Kansas City, with a handful of $10 million to $20 million rounds and one $45 million round, Gutwein said, noting its score increased from 28.4 to 28.
But that wasn’t enough to stop St. Louis’ slide in the rankings — dropping to No. 9 in 2024, down from a high of No. 5 in 2019.
“St. Louis just hasn’t kept up with the speed of other cities’ growth,” Gutwein said. “Columbus, Ann Arbor and Madison are all putting up a lot of growth in startup activity, have more VC funds raised locally and have produced more large rounds.”
Kansas City’s neighbors on the Kansas side also weren’t without criticism. Wichita, Manhattan and Topeka all saw drops in the rankings thanks to inactivity and a lack of big outcomes.
Help on the horizon?
For inspiration, Kansas City can look north to Nebraska — where No. 18 Omaha and No. 20 Lincoln both jumped two positions in the 2024 rankings.
“Both generally boast a higher-than-typical educated workforce, great startup density and Omaha has an unrivaled score for ‘big companies’ compared to any city of its size,” Gutwein said.
But tactically, what can the KC region do to make headway over the next 12 months? The M25 leader shared factors that could become gamechangers:
- Startup count — Launch more startups that get at least the first round of funding (even as little as $250,000 to $500,000; “Give them a fighting chance and get on the map.”
- Investor infusions — Attract both local and external investors to lead 10-plus rounds of $5 million or more each year; putting them on par with the cities with rankings Nos. 6-10
- Big outcomes — Raise at least one $50 million-plus round each year
“And if there’s any government/lobbying work to be done to push both states (Kansas and Missouri) to be more aggressive/competitive with other Midwest states, that would directly push up the government rankings score,” Gutwein said. “But it also indirectly increases the availability of capital and ability of KC startups to raise every round of capital (especially that first pre-seed round).”
Click here to read about Kansas City’s rankings on M25’s 2023 list.

2024 Startups to Watch
stats here
Related Posts on Startland News
Hollywood Animation Academy secures home at Centriq; set to begin first classes in January
Hollywood Animation Academy is leaping from the drawing board to live action in January with its first group of enrolled students. Founded by veteran director and animator Gavin Dell, the trade school is set to prepare students for jobs in the film, gaming, and television industry. Dell, an Overland Park native, returned to Kansas City…
KC duo opens candy shop at Mizzou, bringing familiar flavors to students far from home
COLUMBIA, Missouri — A pair of Mizzou students from the Kansas City area are providing international students on campus with a taste of home. Kogo’s Kandies sells candy and treats from other countries, with the goal of fostering a more inclusive campus environment at the University of Missouri, said co-founders Jacob Burrell-Kogo and Henry Accardo.…
Custom digital avatar tech, affordable housing startup among Scale’s third cohort
Startland News’ Startup Road Trip series explores innovative and uncommon ideas finding success in rural America and Midwestern startup hubs outside the Kansas City metro. This series is possible thanks to the Ewing Marion Kauffman Foundation, which leads a collaborative, nationwide effort to identify and remove large and small barriers to new business creation. COLUMBIA,…
Vytelle doubles its bovine IVF lab capacity; outpacing goals since its $13.2M round
A five-year plan initiated by Vytelle’s Series A funding round called for the agtech startup to double its laboratory capacity to produce bovine embryos through in vitro fertilization. Just a year later, the Lenexa-headquarted company already has opened its fifth new lab. Vytelle’s latest facility — in Franklin, Tennessee — is accessible to beef and dairy…




