This startup leader is revealing entrepreneur answers (and they’re listed in the table of contents)
July 31, 2024 | Nikki Overfelt Chifalu
Aligning the stars as a forward-looking founder and business owner isn’t easy, Maria Flynn noted, so she wrote her own guidebook.
“Entrepreneurs are my tribe of people,” said Flynn, a serial founder and regional digital health leader. “And I was telling the same stories over and over again, so I started to write them down. I realized there’s a book in here somewhere although I didn’t exactly know what it looked like. It was a bit of a puzzle putting these pieces together.”
She released “Make Opportunity Happen” earlier this year.
The founder and CEO of Ambiologix, Flynn knows starting a business can be a lonely journey, she said, expressing her hope the book can let other entrepreneurs know they have a friend.
“I hope the stories resonate with people and provide actionable plans and things they can do. There’s no right way to do this,” said Flynn, who also serves as advisory board chair of Digital Health KC. “I think a lot of times when we read or hear people’s stories, they’re fans of one way to raise money; one way is to handle equity within your company; one one way to do a lot of things.”
“There are a lot of ways to success, but people get overwhelmed by all the different paths that they can take,” she continued.
The book — which Flynn worked on for years — focuses on the stories of three entrepreneurs who didn’t receive much support in the beginning of their journey: Dr. Julio Palmaz, who invented the first successful heart stent; Melanie Perkins of Canva; and James Dyson of Dyson vacuums, she noted.
“It’s very difficult — that’s the common theme — and then they were wildly successful,” Flynn said. “They have this common struggle to get people to walk with them and believe in what they are doing. Then you see these great headlines and you think the stars align for them but not for you. But it’s a lot of work aligning the stars.”
Check out a Startup Hustle podcast interview featuring Maria Flynn and serial founder Matt Watson below, then keep reading.
Flynn — who also led Orbis Biosciences, which exited in 2020 — also details in the book 40 short methods to make opportunity happen in the entrepreneurial world that she’s learned, themed around execution, support system, adapting, and perseverance.
“An example would be urgency builders — because I would think a lot at Orbis: ‘How do I get the other party to go faster? How do I build this urgency to get this done?’” she added. “So it’s five pages and then a template. You can go to the website and download the template and make it relevant to what you’re working on.”
Working with Digital Health KC the past couple of years, Flynn said, is a great example of making opportunity happen by taking the entrepreneurial skill set and putting it in the not-for-profit space.
“You see where you need to go and start taking action to get there,” she explained, noting priorities around raising funding, building teams, and putting structure around goals.
Flynn especially recommends the book for early-stage entrepreneurs, she said.
“This is when you have an idea and you need to get started,” she continued. “Who are the people that you need to surround yourself with? How do you think about making progress and goals? How do you think about how you tell your story?”
Feedback on the book so far has been positive, Flynn said, noting she’s heard that it includes practical advice and is a quick read. She plans to reach out to college and high school entrepreneurship teachers to see how it resonates with those groups.
“When you hear people say, ‘I just looked at the table of contents and this is what I needed to know right now,’ that’s really why you start doing a project like this,” Flynn said.
Featured Business

2024 Startups to Watch
stats here
Related Posts on Startland News
$4M childcare center on Prospect could be pivotal for urban core development
Students who grow up in Kansas City’s urban core shouldn’t be denied access to a quality education based on their address, Myron McCant said as he thumbed through renderings of a 15,000-square-foot learning space that could soon grant such students access to a brighter future. “If you would come into my facility, then you would…
Next KCMO mayor needs this personality trait to build trust, Sly James says
The role of mayor doesn’t always require being “the lead dog on the sled,” said Sly James. Rather, it’s an opportunity for a bridge between those knowledgeable enough to make change, the outgoing KCMO mayor added. “I sit in a position where — let’s say generally, not always — when I call, people call me…
KCMO mayoral vote: Confused? Undecided? Seven FAQs for those still on the bubble
Amid nearly three dozen Kansas City mayoral candidate forums, Startland readers raised a round of questions — some easy to answer, others loaded — but each invested in seeing who will emerge from the shadow of popular, bow tie-wearing mayor, Sly James, to lead KCMO. Here’s a breakdown of the most frequently asked questions about…
Candidates agree: KCMO needs an entrepreneurial mind in the mayor’s office … but what does that mean?
Kansas City was born of an entrepreneurial spirit, said Steve Miller. “We were all in the spirit head of the Westward Expansion, and [were] entrepreneurs from the very beginning,” said Miller, candidate for the Kansas City, Missouri, mayor, last month during the StartupKC Small Business and Entrepreneurship Mayoral Forum. “We need a mayor that has…


