This startup leader is revealing entrepreneur answers (and they’re listed in the table of contents)
July 31, 2024 | Nikki Overfelt Chifalu
Aligning the stars as a forward-looking founder and business owner isn’t easy, Maria Flynn noted, so she wrote her own guidebook.
“Entrepreneurs are my tribe of people,” said Flynn, a serial founder and regional digital health leader. “And I was telling the same stories over and over again, so I started to write them down. I realized there’s a book in here somewhere although I didn’t exactly know what it looked like. It was a bit of a puzzle putting these pieces together.”
She released “Make Opportunity Happen” earlier this year.
The founder and CEO of Ambiologix, Flynn knows starting a business can be a lonely journey, she said, expressing her hope the book can let other entrepreneurs know they have a friend.
“I hope the stories resonate with people and provide actionable plans and things they can do. There’s no right way to do this,” said Flynn, who also serves as advisory board chair of Digital Health KC. “I think a lot of times when we read or hear people’s stories, they’re fans of one way to raise money; one way is to handle equity within your company; one one way to do a lot of things.”
“There are a lot of ways to success, but people get overwhelmed by all the different paths that they can take,” she continued.
The book — which Flynn worked on for years — focuses on the stories of three entrepreneurs who didn’t receive much support in the beginning of their journey: Dr. Julio Palmaz, who invented the first successful heart stent; Melanie Perkins of Canva; and James Dyson of Dyson vacuums, she noted.
“It’s very difficult — that’s the common theme — and then they were wildly successful,” Flynn said. “They have this common struggle to get people to walk with them and believe in what they are doing. Then you see these great headlines and you think the stars align for them but not for you. But it’s a lot of work aligning the stars.”
Check out a Startup Hustle podcast interview featuring Maria Flynn and serial founder Matt Watson below, then keep reading.
Flynn — who also led Orbis Biosciences, which exited in 2020 — also details in the book 40 short methods to make opportunity happen in the entrepreneurial world that she’s learned, themed around execution, support system, adapting, and perseverance.
“An example would be urgency builders — because I would think a lot at Orbis: ‘How do I get the other party to go faster? How do I build this urgency to get this done?’” she added. “So it’s five pages and then a template. You can go to the website and download the template and make it relevant to what you’re working on.”
Working with Digital Health KC the past couple of years, Flynn said, is a great example of making opportunity happen by taking the entrepreneurial skill set and putting it in the not-for-profit space.
“You see where you need to go and start taking action to get there,” she explained, noting priorities around raising funding, building teams, and putting structure around goals.
Flynn especially recommends the book for early-stage entrepreneurs, she said.
“This is when you have an idea and you need to get started,” she continued. “Who are the people that you need to surround yourself with? How do you think about making progress and goals? How do you think about how you tell your story?”
Feedback on the book so far has been positive, Flynn said, noting she’s heard that it includes practical advice and is a quick read. She plans to reach out to college and high school entrepreneurship teachers to see how it resonates with those groups.
“When you hear people say, ‘I just looked at the table of contents and this is what I needed to know right now,’ that’s really why you start doing a project like this,” Flynn said.
Featured Business

2024 Startups to Watch
stats here
Related Posts on Startland News
I am Iron Man: Overland Park startup’s AI mouse brings voice-activated tech to your fingertips
In the Marvel Cinematic Universe, Tony Stark talks to an artificial intelligence program within his Iron Man suit to get immediate access to information — as if he’s having a conversation with AI. Although Stark is a fictional character imbued with vast powers via such tech, Jerry Hsu said, users don’t have to be a…
Chef Dwight Tiller wants to disrupt the macaroni market; up first: he has the Muncheez
A new concept from a popular food truck-turned-food hall chef is more than just a cheesy transition between menus, Dwight Tiller said, it’s an evolution of his journey to bring higher quality and innovation to a culinary category often coated with forgettable flavors. Muncheez — a bold pivot from Tiller’s signature nachos to Kansas City’s mac-and-cheese…
Strang closes doors to Plaza food hall concept, citing slow foot traffic to its diverse, chef-driven menus
Despite a bustling holiday shopping season on the Country Club Plaza, a food hall in the iconic Kansas City shopping district failed to gain a foothold, said CEO Shawn Craft, announcing the closure of another Strang Hall location less than a month after shuttering its downtown space. Leaders behind Strang Chef Collective on the Plaza…
Well Played, KC: How an overseas Chiefs game inspired designs that brought Lindsey Hall off the bench
Her apparel brand’s timeless style echoes Ralph Lauren’s aesthetic, with a KC twist Kansas City’s fashion scene has gained a new player in Well Played KC, a lifestyle brand blending classic Americana style with local pride. Founded by Lindsey Hall, the business is gaining momentum with versatile, throwback-that-doesn’t-feel-dated apparel that resonates with on-the-go Kansas Citians. …


