A high-tech funder planted seeds in 135+ Missouri startups; three bloomed into $1B+ unicorns in the past six months
May 13, 2021 | Tommy Felts
When news broke this week that St. Louis-based plant tech firm Benson Hill reached a $2 billion valuation, it marked the third “unicorn” minted among MTC-funded companies in the past six months, said Jack Scatizzi.
“Early-stage investing takes patience and the results can’t be rushed,” said Scatizzi, executive director of the Missouri Technology Corporation, noting MTC’s first investment in Benson Hill came in 2013 — about eight years before the company’s headline-making announcement.
MTC is a public-private partnership created by the Missouri General Assembly to promote entrepreneurship and foster the growth of new and emerging high-tech companies. To date, it has made direct investments of just under $44 million into more than 135 early-stage Missouri-based high growth technology-focused companies, which have raised more than $1 billion in additional private capital.
Benson Hill — a food technology company that uses artificial intelligence, data and a variety of breeding techniques to create innovative food and ingredient products — announced its merger Monday with Star Peak Corp II, a special-purpose acquisition company, a process which resulted in the valuation at $2 billion.
Elements derived from Benson Hill’s technology are key for plant-based meat alternatives, as well as in-the works animal feed — both expected to be crucial in the fight against climate change, according to a report in the Wall Street Journal.
MTC invested $175,000 in Benson Hill’s initial seed round, which led to the company putting the bulk of its operations in Missouri (St. Louis). The organization made additional investments in Benson Hill’s Series A and Series B rounds, as well as participated in company-sponsored stock buyback programs to ensure that the state’s initial investment was returned to be redistributed throughout the state’s entrepreneurial ecosystems, Scatizzi said.
“Early-stage funding is critical to the success of companies and is typically the hardest capital to find,” he explained. “Once a product has completed research and development or beta testing and the company has demonstrated a commercial need for the product, specifically the ability to find customers willing to pay for the product/service, there are more sources of capital available.”
Click here to see MTC’s full portfolio.
Among the Kansas City startups to take advantage of MTC’s co-investment funding: backstitch, Little Hoots, Moblico, Mycroft, Pathfinder Health Innovations, PayIt, Popbookings, Proviera Biotech, SCD Probiotics, Sickweather, SoftVu, StoryUp, Transportant, Venture360, and VideoFizz. Today, many of these startups are now listed among Kansas City’s Top VC-Backed Companies.
That’s why MTC’s role — at the beginning of the journey — is so critical to the continued development of the state’s entrepreneurs and business ecosystems, Scatizzi said.
The Benson Hill valuation comes on the heels of two other recent unicorn announcements from MTC-funded companies, he added. A “unicorn” is a startup valued at $1 billion or more.
St. Louis startup Gainsight was acquired by Vista Equity Partners for $1.1 billion in December. And Aclaris Therapeutics, a Pennsylvania biopharmaceutical company with significant ties back to St. Louis, posted positive Phase 2a clinical trial data and its market cap broke at $1 billion in January, according to Scatizzi.
Those wins didn’t happen overnight, he added.
MTC first invested in Gainsight (formerly Jbara Software ) in 2012. It funded Confluence Life Science — later acquired by Aclaris Therapeutics — in 2011.
“MTC’s investment and the matching private funds are leveraged by companies to de-risk the investment opportunity so that it will become more attractive to sources of later-stage capital,” Scatizzi said. “The more investment opportunities that MTC can help de-risk, the more growth capital that will be invested into Missouri which will create a significant economic development impact.”
In some respects, Scatizzi continued, the trio of unicorn companies offer an even more sizable bump to Missouri than to their own bottom lines.
Gainsight and Aclaris both have offices/labs in the St. Louis area. And at the time Benson Hill opened its new $52 million headquarters in St. Louis, the company had more than 180 employees with at least 20 open positions, CEO Matt Crisp.
Their success stories are major highlights, but only showcase a portion of MTC’s impact, the program’s leader detailed. MTC published a summary of economic development findings this spring after surveying more than 70 of its portfolio companies.
Click here to read the summary, which delves deeper into MTC’s distribution across markets, commercialization of products by portfolio companies, job creation, investor interest, and diversity of leadership.
For example, MTC’s more than 135 portfolio companies have created more than 320 commercial products and generated more than $277 million in total revenues for the previous fiscal year (July 1, 2019 to June 31, 2020), according to the data. The portfolio also has created more than 480 new jobs, and employed more than 1,000 people during the same fiscal year period.
That feeds an ongoing funding cycle for Missouri and its entrepreneurs, Scatizzi said, noting MTC has generated more than $11 million in returns — meaning about a quarter of the capital invested has already been returned to the organization, allowing MTC to redistribute to the state’s entrepreneurial ecosystems.
Featured Business

2021 Startups to Watch
stats here
Related Posts on Startland News
Tariffs are driving up costs for American coffee roasters: ‘We’ve never seen anything like this’
Editor’s note: The following story was published by Harvest Public Media and KCUR, Kansas City’s NPR member station, and a fellow member of the KC Media Collective. Click here to read the original story or here to sign up for KCUR’s email newsletter. Coffee has gotten a lot more expensive in the U.S. as tariffs seep into the price tag;…
Kiva KC brings zero-interest microloans to founders shut out of traditional capital
Editor’s note: The Economic Development Corporation of Kansas City (EDCKC) and KC BizCare are partners of Startland News. Kansas City is betting that a global microlending model — one built on $25 contributions and community belief in everyday entrepreneurs — can help close one of the city’s most stubborn gaps: early-stage capital for founders who…
How this startup (and a KC sports icon) turned young players into card-carrying legends overnight
An Overland Park-based custom trading card company and a Kansas City soccer star are teaming up on the pitch with a goal to make youth sports fun again. Stat Legend — launched by Chris Cheatham and Nick Weaver in 2023 — created custom cards for all 250 players who suit up for the Captains Soccer…
How the 2025 Kansas Citians of the Year proved ‘KC Made’ could compete against the world
They recognized Kansas City’s promise and potential early — helping usher in a new era of global sports opportunity for the region. Now Cliff Illig and Kathy Nelson are the latest community shapers crowned Kansas Citians of the Year. Honored Tuesday night during the Greater Kansas City Chamber of Commerce’s annual dinner, the two were…



